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Synthesis and spectral study of a novel distamycin conjugate

✍ Scribed by M. J. Pineda de las Infantas; J. Campos; P. G. Baraldi; R. Romagnoli; M. A. Gallo; A. Espinosa

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
92 KB
Volume
41
Category
Article
ISSN
0749-1581

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✦ Synopsis

Abstract

The ^1^H and ^13^C NMR resonances for a novel distamycin conjugate, 3‐[1‐methyl‐4‐[1‐methyl‐4‐[1‐methyl‐4‐[N^1^‐[5‐methyl‐2,4(1__H__,3__H__)pyrimidinedione]acetylamino]pyrrole‐2‐carboxamido]pyrrole‐2‐carboxamido]pyrrole‐2‐carboxamido]propionamidine hydrochloride (1), were assigned, using the concerted application of one‐ and two‐dimensional NMR techniques including nuclear Overhauser effect difference, DEPT, HMQC and HMBC experiments. Copyright © 2003 John Wiley & Sons, Ltd.

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