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Facile Synthesis of Novel 5-Amino 1,3-Disubstituted Tetrahydropyrimidinones.

✍ Scribed by Guanglin Luo

Publisher
John Wiley and Sons
Year
2005
Weight
21 KB
Volume
36
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

For Abstract see ChemInform Abstract in Full Text.

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## Abstract The reaction of hydrazide with carbonyl chloride in the presence of sodium carbonates leads to the corresponding 1,2‐diacylhydrazines [**1a**–**t**, R^1^C(O)NHNHC(O)R^2^, R^1^ = aryl, R^2^ = aryl or alkyl] in moderate to excellent yield (57–90 %). The latter reacts with 2,4‐diphenyl‐1,3