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Facile synthesis of a selectively protected triazamacrocycle

✍ Scribed by Renato T. Skerlj; Siqiao Nan; Yuanxi Zhou; Gary J. Bridger

Book ID: 104252024
Publisher: Elsevier Science
Year: 2002
Tongue: French
Weight: 108 KB
Volume: 43
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)01756-2

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✦ Synopsis

1,7-Diaminoheptane was selectively homologated with the novel reagent N-(2-nitrobenzenesulfonyl)aziridine. A series of reactions then followed to afford a selectively protected 14-membered triazamacrocyclic ring.

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