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Facile synthesis of 4-substituted pyridines using grignard reagents

✍ Scribed by Kin-ya Akiba; Yuji Iseki; Makoto Wada

Publisher: Elsevier Science
Year: 1982
Tongue: French
Weight: 140 KB
Volume: 23
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)87747-3

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✦ Synopsis

N-t-Butyldlmethylsilylpyridinmm triflate (5) reacted with Grignard reagents at 4-posltlon with almost complete regloselectlvlty (299% ) to afford the corresponding

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