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Facile synthesis of 4-substituted 3a,4,5,9b-tetrahydrobenz[e]isoindoline

โœ Scribed by Paull, Kenneth D.; Cheng, C. C.


Book ID
127161296
Publisher
American Chemical Society
Year
1972
Tongue
English
Weight
490 KB
Volume
37
Category
Article
ISSN
0022-3263

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A facile, solvent free, ecofriendly approach for the synthesis of 2-amino-3(ethylcarboxy)-4,6-disubstituted pyridine 4 and pyrazolo [3,4-b]pyridines 6 is herein described employing neat reaction conditions under microwave irradiation. This solventless methodology is environmentally benign as it comp