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Facile Synthesis and In-Vitro Antitumor Activity of Some Pyrazolo[3,4-b]pyridines and Pyrazolo[1,5-a]pyrimidines Linked to a Thiazolo[3,2-a]benzimidazole Moiety

✍ Scribed by Hatem A. Abdel-Aziz; Tamer S. Saleh; Heba S. A. El-Zahabi

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
515 KB
Volume
343
Category
Article
ISSN
0365-6233

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## Abstract magnified image __E__‐3‐(__N,N__‐Dimethylamino)‐1‐(3‐methylthiazolo[3,2‐__a__]benzimidazol‐2‐yl)prop‐2‐en‐1‐one (**2**) was synthesized by the reaction of 1‐(3‐methylthiazolo[3,2‐__a__]benzimidazol‐2‐yl)ethanone (**1**) with dimethylformamide‐dimethylacetal. The reaction of **2** with