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Facile Preparation of N-Acyl-2-(diethoxyphosphoryl)glycine Esters and Their Use in the Synthesis of Dehydroamino Acid Esters

✍ Scribed by Prof. Dr. Ulrich Schmidt; Dr. Albrecht Lieberknecht; Ute Schanbacher; Thomas Beuttler; Jochen Wild


Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
234 KB
Volume
21
Category
Article
ISSN
0044-8249

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Papain catalyzed synthesis of glyceryl e
✍ Yuri V. Mitin; Karin Braun; Peter Kuhl πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 113 KB πŸ‘ 2 views

Papain catalyzed synthesis of glyceryl esters of BOC(Z)-protected amino acids and peptides was performed at 40-50Β°C in a 50 molar excess of glycerol. Equilibrium was achieved in 6-7 h. The maximal yield of esters (50-70%) was obtained at 10% of water and pH 3.2-3.4. A lower water concentration resul