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Facile Preparation of Chiral 1, 3-Diols via Stereoselective Transfer Hydrogenation of 1, 3-Diones

โœ Scribed by Ying-Chun Chen; Jin-Gen Deng; Tong-Fei Wu; Xta Cui; Yao-Zhong Jiang; Michael C. K. Choi; Albert S. C. Chan


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
258 KB
Volume
19
Category
Article
ISSN
0256-7660

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Facile synthesis of 4-alkoxycarbonylisoq
โœ Muriel Billamboz; Fabrice Bailly; Philippe Cotelle ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 126 KB ๐Ÿ‘ 1 views

## Abstract magnified image A series of 4โ€methoxycarbonylisoquinolineโ€1,3โ€diones was obtained from homophthalic acid in four steps. The key step was the quantitative and rapid alkaline cyclization of 2โ€methoxycarbonylโ€2โ€(2โ€methoxycarbonylphenyl) acetamides. Homologation easily afforded in the same