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Facile one-pot method for the synthesis of novel glycosylidene-based quinolines

✍ Scribed by Peter H. Dobbelaar; Cecilia H. Marzabadi

Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
239 KB
Volume
51
Category
Article
ISSN
0040-4039

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✦ Synopsis

A one-pot approach to the synthesis of novel glycosylidene-based quinolines is described. The reaction involves a Lewis acid catalyzed Povarov addition followed by oxidation of the resulting spiroanellated tetrahydroquinoline intermediates to yield the open-ring glycosylidene-derived quinoline.

πŸ“œ SIMILAR VOLUMES

A novel method for the facile synthesis
A novel method for the facile synthesis of depsipeptides
✍ Chaim Gilon; Yakir Klausner; Alfred Hassner πŸ“‚ Article πŸ“… 1979 πŸ› Elsevier Science 🌐 French βš– 174 KB

A one pot, high yield synthesis of depsipeptides is described involving room temperature condensation of hindered substrates (N-BOC amino acids and benzyl cc-hydroxy esters) in the presence of DCC and a dialkylaminopyridine. lo. 40 5. M. M.