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Facile Creation of 3-Indolyl-3-hydroxy-2-oxindoles by an Organocatalytic Enantioselective Friedel–Crafts Reaction of Indoles with Isatins

✍ Scribed by Jing Deng; Shilei Zhang; Peng Ding; Hualiang Jiang; Wei Wang; Jian Li


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
190 KB
Volume
352
Category
Article
ISSN
1615-4150

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✍ Emmanuel Riguet 📂 Article 📅 2012 🏛 John Wiley and Sons ⚖ 58 KB 👁 1 views

## Abstract The prolinol‐catalyzed treatment of indoles with the furanone (II) followed by reduction and lactonization provides an efficient approach to chiral lactones of type (III) and (IX).