Facile conversion of racemic ibuprofen to (S)-ibuprofen
โ Scribed by David Chavez-Flores; James M. Salvador
- Book ID
- 113929654
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 326 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0957-4166
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Ibuprofen (ibu) is a racemic 2-arylpropionic acid non-steroidal anti-inflammatory drug whose activity is due mainly to the S-enantiomer. So far only the racemic compound is in clinical use. A double-blind randomized trial was carried out for a 2-week period in 50 patients with classical rheumatoid a
In vitro experiments to investigate possible stereoselective aspects of the topical administration of ibuprofen have been conducted. Incubation of ibuprofen with rat skin homogenates in the presence of coenzyme A, ATP, and magnesium provided no evidence for the formation of ibuprofenyl coenzyme A (t