Two new vitamin D 2 analogues, (22Z)-25-(
Facile and stereoselective synthesis of 25-hydroxyvitamin d2
β Scribed by Sachiko Yamada; Masami Shiraishi; Masayuki Ohmori; Hiroaki Takayama
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- French
- Weight
- 162 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
Extraction, lipid-reduction, and chromatographic methods suitable for the resolution and subsequent quantitation of vitamin D2, vitamin D3, 25-hydroxyvitamin D2, and 25-hydroxy-vitamin D3 from human milk are described. This procedure utilizes a methanol:methylene chloride extraction, precipitation o
Preparations of the titled fluorinated vltamln D 2 analogs (2, 2 and 2) were efflclently achieved through reactions of the C22 -aldehyde C,$) with phenylsulfone derivatives (z, ,8 and 2). As in the case of vitamin D 3\*l it was demonstrated that vitamin D2 must be metabolically hydroxylated at C-25