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Facile and chemoselective reduction of carboxylic acids to alcohols using BOP reagent and sodium borohydride

✍ Scribed by Ross P. McGeary


Book ID
108386704
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
243 KB
Volume
39
Category
Article
ISSN
0040-4039

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Several carboxylic acids, including N-Boo, N-Cbz and N-Fmoe amino acids were reduced to the corresponding alcohols by activation of the carboxy function with cyanuric chloride and N-methylmorpholine followed by reduction with aqueous sodium borohydride.