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F.93. Modulation of Autoantibody Glycosylation during Arthritis in the K/BxN Mouse

✍ Scribed by Melissa Hazen; Shannon McArdel; Altan Ercan; Adriana Ortiz-Lopez; Christophe Benoist; Diane Mathis; David Lee


Book ID
113541104
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
37 KB
Volume
131
Category
Article
ISSN
1090-2341

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## Abstract ## Objective Osteopontin (OPN) is a secreted glycoprotein involved in a range of physiologic processes, including inflammation, immunity mediated by Th1 cells, and bone remodeling. It is expressed in the joints of rheumatoid arthritis patients and has been the subject of conflicting re