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F.131. Regulatory T-Cells in Colorectal Cancer Suppress Immune Function and Anti-Tumor Activity

โœ Scribed by Karen Henjum; Sheraz Yaqub; Milada Mahic; Aandahl Einar; Frode Jahnsen; Bjorn Bjornbeth; Kjetil Tasken


Book ID
113539147
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
43 KB
Volume
119
Category
Article
ISSN
1090-2341

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The NKG2D receptor is expressed by human NK, gammadelta T and alpha/beta T lymphocytes and its engagement results in the stimulation of effector cells. We evaluated the role of NKG2D receptor in anti-colorectal cancer (CRC) immune response. The cell surface expression of stress-inducible NKG2D ligan