High frequency of tumor-infiltrating FOX
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Daniel M. Frey; Raoul A. Droeser; Carsten T. Viehl; Inti Zlobec; Alessandro Lugl
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Article
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2010
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John Wiley and Sons
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French
⚖ 331 KB
👁 1 views
Regulatory T cells (T reg ) inhibit the generation of host-versus-tumor immunity via suppression of tumor-specific effector T-cell responses and development of immune tolerance to neoplastic cells. The transcription factor forkhead box P3 (FOXP3) is an intracellular key molecule for T reg developmen