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F127/Calcium phosphate hybrid nanoparticles: a promising vector for improving siRNA delivery and gene silencing

✍ Scribed by Qin, Liubin; Sun, Ying; Liu, Peifeng; Wang, Qi; Han, Baosan; Duan, Yourong

Book ID
126649915
Publisher
Taylor and Francis Group
Year
2013
Tongue
English
Weight
397 KB
Volume
24
Category
Article
ISSN
0920-5063

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✍ Y. Kakizawa; K. Miyata; S. Furukawa; K. Kataoka 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB 👁 1 views

**Poly(ethylene glycol) (PEG)‐covered hybrid particles** (see Figure) of calcium phosphate (CaP), and plasmid DNA (pDNA) have been prepared in a size‐controllable manner in the presence of a block copolymer. The particles show a substantial colloidal stability as well as tolerance of entrapped pDNA