Extremely high prevalence of DNASE1*1 allele in African populations
β Scribed by Haruo Takeshita; Junko Fujihara; Mikiko Soejima; Yoshiro Koda; Toshihiro Yasuda; Tamiko Nakajima
- Book ID
- 101815852
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 55 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0263-6484
- DOI
- 10.1002/cbf.1414
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Multiple variants of the vascular adhesion molecule-1 (VCAM1) promoter show increased nucleotide heterozygosity in the African American population. Using a novel transfection-based transcriptional pathway profiling method, we show that select uncommon variants are functionally hyperactive. Eight can
Alpha-1-antitrypsin (PI) phenotypes were studied in a sample of 450 Tunisians. The observed frequencies of PI alleles were identical to those in African populations, with a very low incidence of PI\*S and virtual absence of PI\*Z. Such figures are similar to estimates in Asians and clearly opposite