✦ LIBER ✦

Absence of the alpha-1-antitrypsin PI*Z allele in Tunisia substantiates the particular genetic structure of African populations

✍ Scribed by S. Makni; M. Zitouni; K. Ayed; S. Mhirii; S. Azabi; F. Cherif; M. Maalej; J.P. Martin; R. Sesboüé

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 40 KB
Volume: 9
Category: Article
ISSN: 1042-0533
DOI: 10.1002/(sici)1520-6300(1997)9:2<223::aid-ajhb8>3.0.co;2-0

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✦ Synopsis

Alpha-1-antitrypsin (PI) phenotypes were studied in a sample of 450 Tunisians. The observed frequencies of PI alleles were identical to those in African populations, with a very low incidence of PI*S and virtual absence of PI*Z. Such figures are similar to estimates in Asians and clearly opposite to those in Europeans. Am. J. Hum. Biol. 9:223-224, 1997. © 1997 Wiley-Liss, Inc.