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Extrathymic human t lymphocyte development and regulation in immune deficient mice

โœ Scribed by X. Wang; R. Hong; J. Nolta


Book ID
114216533
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
14 KB
Volume
28
Category
Article
ISSN
0301-472X

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T cell development and function in CrkL-
โœ Amyโ€„C. Peterson; Reinhardโ€„E. Marks; Patrickโ€„E. Fields; Akira Imamoto; Thomasโ€„F. ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 257 KB

## Abstract The adapter protein CrkL has been implicated in multiple signal transduction pathways in hematopoietic cells. In Tโ€„lymphocytes, the recruitment of CrkLโ€C3G complexes has been correlated with hyporesponsiveness, implicating CrkL as a potential negative regulator. To test this hypothesis