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Extrapancreatic and pancreatic actions of glibenclamide in rats

✍ Scribed by W. Heptner; A. Zermatten; H. -M. Kellner; O. Christ; J. -P. Felber

Publisher
Springer
Year
1977
Tongue
English
Weight
505 KB
Volume
13
Category
Article
ISSN
0012-186X

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As judged by autoradiographic criteria at the optical level, rat islet cells progressively accumulate 3H-glibenclamide over 1 to 30 min incubation at 24 degrees C. The labeled material associates with all endocrine cells, but is preferentially seen within B cells. The total uptake of 3H-glibenclamid