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Extrapancreatic effect of glibenclamide: Stimulation of duodenal insulin-releasing activity (DIRA) in man

✍ Scribed by A. Zermatten; W. Heptner; B. Delaloye; R. Séchaud; J. -P. Felber


Publisher
Springer
Year
1977
Tongue
English
Weight
373 KB
Volume
13
Category
Article
ISSN
0012-186X

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The effects of a sulphonylurea, gliquidone, on insulin binding and the insulin induced rate of glycogen synthesis, were studied in rat hepatocytes in primary culture. Hepatocytes were cultured for 48 h. During the second 24 h of this period, the hepatocytes were incubated with or without gliquidone