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Extrahepatic sulfation and glucuronidation in the rat in vivo: Determination of the hepatic extraction ratio of harmol and the extrahepatic contribution to harmol conjugation

✍ Scribed by Gerard J. Mulder; Jeannette G. Weitering; Egbert Scholtens; Janet R. Dawson; K.Sandy Pang


Book ID
115777835
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
561 KB
Volume
33
Category
Article
ISSN
0006-2952

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Glutathione conjugation of bromosulfopht
✍ C. A. Wilco Snel; K. Sandy Pang; Gerard J. MulderD πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 980 KB

The relation between the rate of glutathione (GSH) conjugation and hepatic GSH content was studied in the rat in uiuo and the in situ single-pass-perfused rat liver preparation with bromosulfophthalein (BSP) as the model substrate. The biliary excretion of the BSP-GSH conjugate and the hepatic GSH c