𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Extrahepatic Sites of Metabolism of Halothane in the Rat

✍ Scribed by Ghantous, Hunan ;Löfberg, Boël ;Tjälve, Hans ;Danielsson, Bengt R. G. ;Dencker, Lennart


Book ID
114801143
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
971 KB
Volume
62
Category
Article
ISSN
0901-9928

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


EXTRAHEPATIC FIRST-PASS METABOLISM OF NI
✍ JOHN S. GRUNDY; LISE A. ELIOT; ROBERT T. FOSTER 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 170 KB 👁 2 views

The peroral (po) bioavailability of nifedipine is reported to range from about 45 to 58% in the rat; this compares favourably to human beings. The metabolism of nifedipine is similar in rats and humans (oxidation of the dihydropyridine ring), with the liver believed to be solely responsible for the

Respective roles of hypoxia and halothan
✍ Hitoshi Hatano; Fumio Nomura; Kunihiko Ohnishi; Toshihiko Iijima; Akira Hayasaka 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 447 KB

To evaluate the respective roles of halothane metabolism and hypoxia in rats with halothane hepatotoxicity, experiments were designed with special reference to blood gas. After pretreatment with phenobarbital (80 mg per kg., i.p.) for four consecutive days, rats were exposed to 1.0% halothane under