Extragonadal germ cell tumors in brothers
β Scribed by D'Silva, Stany A.; Williamson, Stephan K.; Schimke, R. Neil
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 3 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0148-7299
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β¦ Synopsis
Germ cell neoplasms are uncommon. Most are of gonadal origin with only a small proportion developing in extragonadal sites. Recently we saw primary mediastinal germinomas in brothers.
π SIMILAR VOLUMES
In patients with primary germ cell tumors, treatment with combination chemotherapy followed by surgical debulking of residual tissue usually produces favorable results. The best treatment for patients with extragonadal germ cell tumors ( E m ) remains a problem. In our series of 12 patients, importa
A retrospective analysis was performed on all patients diagnosed with biopsyproven extragonadal germ cell tumors at the University of Virginia (Charlottesville, VA), The Medical University of South Carolina (Charleston, SC), the Bethesda Naval Hospital (Bethesda, MD), and The Medical College of Virg
Thirty patients with germ cell tumors originating in the mediastinum are reviewed and analyzed (20 embryonal carcinomas and 10 seminomas). Local control of the disease was successful by resection and/or external radiation in patients with seminoma; 50% were alive and well at 10 years. Patients with