A new asymmetric route to synthetically
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Jarosław Kiegiel; Jacek Nowacki; Aldona Tarnowska; Małgorzata Stachurska; Janusz
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Article
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2000
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Elsevier Science
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French
⚖ 100 KB
The results of asymmetric hydrogenation of diethyl 3,4-dioxohexanedioate are presented. (R,R)-1,5-Dioxa-2,6-dioxobicyclo[3.3.0]octane, the product of hydrogenation and subsequent cyclization, was obtained in high enantiomeric excess. This compound was transformed into synthetically useful (R)-4-hydr