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Extracellular signal-regulated protein kinase activation in spinal cord contributes to pain hypersensitivity in a mouse model of type 2 diabetes

✍ Scribed by Xu, Xiang; Chen, Hui; Ling, Bing-Yu; Xu, Lan; Cao, Hong; Zhang, Yu-Qiu


Book ID
121563433
Publisher
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
Year
2013
Tongue
English
Weight
935 KB
Volume
30
Category
Article
ISSN
1673-7067

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## Abstract Glial cell line‐derived neurotrophic factor (GDNF) has been shown to be neuroprotective in animal models of the dopamine deficiency in Parkinson's disease. To examine the role of the extracellular signal‐regulated kinases 1 and 2 (ERK1/2) in this process, we infused a single dose of GDN