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Ca2+/calmodulin-dependent protein kinase II in the spinal cord contributes to neuropathic pain in a rat model of mononeuropathy

✍ Scribed by Yi Dai; Hu Wang; Akiko Ogawa; Hiroki Yamanaka; Koichi Obata; Atsushi Tokunaga; Koichi Noguchi

Book ID: 109023921
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 479 KB
Volume: 21
Category: Article
ISSN: 0953-816X
DOI: 10.1111/j.1460-9568.2005.04091.x

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## Abstract Hyperglycemia and acidosis are the key factors in diabetic complications. It has been shown that acute or chronic diabetes alters serotonin levels in brain. However, the mechanism of hyperglycemia‐ or acidosis‐induced changes in serotonin levels remains poorly understood. Because Ca^2+^