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Extracellular origin of the lipid lysosomal storage in cultured fibroblasts from Wolman's disease

✍ Scribed by Robert SALVAYRE; Anne NEGRE; Arlette MARET; Jean RADOM; Louis DOUSTE-BLAZY


Book ID
115125514
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
635 KB
Volume
170
Category
Article
ISSN
1432-1327

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## ABSTRACT Immunofluorescence microscopy shows that unlike cytoplasmic microtubules (MT), vimentin‐type intermediate filaments (IF) are collected into ring‐shaped structures in affected fibroblasts. The altered IF organization could be observed in monolayers of polarized fibroblasts in the prolong