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Extracellular matrix stoichiometry in osteoblasts from patients with osteogenesis imperfecta

✍ Scribed by Neal S. Fedarko; Pamela Gehron Robey; Ulrich K. Vetter

Book ID
112119504
Publisher
American Society for Bone and Mineral Research
Year
2009
Tongue
English
Weight
881 KB
Volume
10
Category
Article
ISSN
0884-0431

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## Abstract We studied the expression of osteoblastic markers in cultured cells isolated from the bone of 15 patients with different clinical forms of osteogenesis imperfecta (OI) and of seven fetal and postnatal controls. Cultured bone cells of ten OI patients produced abnormal collagen type I. Si