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Extracellular ATP attenuates ischemia-induced caspase-3 cleavage in human endothelial cells

✍ Scribed by D. Urban; F.V. Härtel; K. Gadiraju; D. Gündüz; M. Aslam; H.M. Piper; T. Noll

Book ID: 116303771
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 663 KB
Volume: 425
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2012.07.073

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## Abstract We have previously reported that interferon‐α (IFNα) induces apoptosis and EGF can antagonize this effect in human epidermoid cancer KB cells. Since apoptosis occurs together with cytoskeleton reorganization we have evaluated if IFNα and EGF could modulate cell remodeling in our experim