Extra genes, in and out of chromosomes
โ Scribed by Gall, Joseph G.
- Book ID
- 109727385
- Publisher
- Nature Publishing Group
- Year
- 1982
- Tongue
- English
- Weight
- 116 KB
- Volume
- 298
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/298875a0
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## Abstract We previously showed that plasmids containing a mammalian replication initiation region and a matrix attachment region were efficiently amplified to few thousand copies per cell, and that they formed extrachromosomal double minutes (DMs) or chromosomal homogeneously staining regions (HS