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External globus pallidus stimulation modulates brain connectivity in Huntington's disease

✍ Scribed by Ligot, Noémie; Krystkowiak, Pierre; Simonin, Clémence; Goldman, Serge; Peigneux, Philippe; Van Naemen, John; Monclus, Michel; Lacroix, Simon Frédéric; Devos, David; Dujardin, Kathy

Book ID
109871494
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
341 KB
Volume
31
Category
Article
ISSN
0271-678X

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## Abstract Bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) was performed in a patient with Huntington's disease (HD) with severe chorea. Stimulation at 40 and 130Hz improved chorea. Stimulation at 130Hz slightly worsened bradykinesia overall, whereas 40Hz had little effect. A