A model was developed to detect effects of quantitative trait loci (QTLs) in sibships from simulated nuclear family data using the full covariance structure of the data and analyzing all five quantitative traits simultaneously in a multivariate model. Evidence of the presence of loci was detected on
โฆ LIBER โฆ
Extensions to pedigree analysis. IV. Covariance components models for multivariate traits
โ Scribed by Lange, Kenneth ;Boehnke, Michael ;Opitz, John M.
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 564 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0148-7299
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## Abstract We describe a new program lm\_twoqtl, part of the MORGAN package, for parametric linkage analysis with a quantitative trait locus (QTL) model having one or two QTLs and a polygenic component, which models additional familial correlation from other unlinked QTLs. The program has no restr