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Extended hildebrand solubility approach: Sulfonamides in binary and ternary solvents

✍ Scribed by A. Martin; P. L. Wu; T. Velasquez


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
626 KB
Volume
74
Category
Article
ISSN
0022-3549

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Extended hildebrand solubility approach:
✍ A. Martin; P. L. Wu; A. Adjei; M. Mehdizadeh; K. C. James; Carl Metzler πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 831 KB

value for 8-chloro-6-phenyl-4H-s-triazolo[4,3-a J\1,4] benzodiazepine (estazolam) was reported to be 2.84 from the UV absorption spectral change (23). Considering the structural difference mentioned, the estimated pKa value for triazolam, 1.52, is reasonable. The bioavailability or the pharmacologi