better if the lactate dehydrogenase value was withdrawn from the staging system proposal. Clinical staging systems are developed to provide accurate prognostic information for diagnostic therapeutic decision-making and, moreover, to facilitate communication between clinicians. Therefore, clinical s
✦ LIBER ✦
Expressions of hypoxia-inducible factor-1α and hexokinase-II in gastric adenocarcinoma: the impact on prognosis and correlation to clinicopathologic features
✍ Scribed by Miao-zhen Qiu; Bing Han; Hui-yan Luo; Zhi-wei Zhou; Zhi-qiang Wang; Feng-hua Wang; Yu-hong Li; Rui-hua Xu
- Publisher
- S. Karger AG
- Year
- 2010
- Tongue
- English
- Weight
- 438 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1010-4283
No coin nor oath required. For personal study only.
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## Background: Hypoxia-inducible factor (hif)1 alpha is considered to play a key role in the adaptation of cells to hypoxia by stimulating angiogenesis via regulation of vascular endothelial growth factor and by metabolic adaptation to o(2) deprivation. ## Methods: Expression of hif-1 alpha prote