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Expression, purification, and characterization of the Kunitz-type proteinase inhibitor domain of the amyloid β-protein precursor-like protein-2

✍ Scribed by William E. Van Nostrand; Alvin H. Schmaier; Barry R. Neiditch; Robert S. Siegel; William C. Raschke; Sangram S. Sisodia; Steven L. Wagner


Book ID
113269474
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
484 KB
Volume
1209
Category
Article
ISSN
0167-4838

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Evolutionary origin of a Kunitz-type try
✍ Kazuho Ikeo; Kei Takahashi; Takashi Gojobori 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 716 KB

The Kunitz-type protease inhibitor is one of the serine protease inhibitors. It is found in blood, saliva, and all tissues in mammals. Recently, a Kunitz-type sequence was found in the protein sequence of the amyloid beta precursor protein (beta APP). It is known that beta APP accumulates in the neu