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Amyloid βprotein precursors with kunitz-type inhibitor domains and acetyl-cholinesterase in cerebrospinal fluid from patients with dementia of the Alzheimer type

✍ Scribed by K. Urakami; K. Takahashi; H. Saito; A. Okada; S. Nakamura; S. Tanaka; N. Kitaguchi; Y. Tokushima; S. Yamamoto


Book ID
114783615
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
356 KB
Volume
85
Category
Article
ISSN
0001-6314

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Evolutionary origin of a Kunitz-type try
✍ Kazuho Ikeo; Kei Takahashi; Takashi Gojobori 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 716 KB

The Kunitz-type protease inhibitor is one of the serine protease inhibitors. It is found in blood, saliva, and all tissues in mammals. Recently, a Kunitz-type sequence was found in the protein sequence of the amyloid beta precursor protein (beta APP). It is known that beta APP accumulates in the neu