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Expression Patterns of Cyclins D1, E and Cyclin-Dependent Kinase Inhibitors p21(Waf1/Cip1) and p27(Kip1) in Urothelial Carcinoma: Correlation with Other Cell-Cycle-Related Proteins (Rb, p53, Ki-67 and PCNA) and Clinicopathological Features

✍ Scribed by Ioachim, E.; Michael, M.; Stavropoulos, N.E.; Kitsiou, E.; Hastazeris, K.; Salmas, M.; Stefanaki, S.; Agnantis, N.J.


Book ID
121299056
Publisher
S. Karger AG
Year
2004
Tongue
English
Weight
272 KB
Volume
73
Category
Article
ISSN
0042-1138

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The expression and prognostic role of cyclin D1, cyclin E, and p21 (WAF1/CIP1) were immunohistochemically investivated in 413 curatively resected gastric carcinomas. p21 was expressed in 65β€’4 per cent (n=270), cyclin D1 in 23β€’7 per cent (n=98), and cyclin E in 13β€’6 per cent (n=56) of the tumours. Th