Infection of non-UV-irradiated cells of Salmonella typhimurium with UVdamaged P22 or KB 1 phage induces reeA-dependent inhibition of cell division, cell mutagenesis and prophage induction but not inhibition of respiration. On the contrary, respiration and ATP concentration are increased after treatm
Expression ofrecA-gene dependent SOS functions inSalmonella typhimurium
✍ Scribed by R. Guerrero; J. Barbé
- Book ID
- 104759873
- Publisher
- Springer Netherlands
- Year
- 1982
- Tongue
- English
- Weight
- 403 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0003-6072
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✦ Synopsis
Thymine starvation of RecA + Thy-strains of Salmonella typhimurium does not induce the inhibition of cellular respiration, one of the recA-gene dependent SOS functions. Nevertheless, thymine deprivation is able to produce a normal induction of prophage and thymineless death in these same strains. However, when these mutants are treated, in the presence of thymine, with UVirradiation or bleomycin, they show a normal inhibition of cellular respiration and other SOS functions. Thus, one injurious treatment (thymine deprivation) may trigger prophage induction but not cessation of respiration, whereas another agent (UV-irradiation) may induce both. Together, these results suggest a possible discrimination in the pathways and conditions of expression of various SOS functions.
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