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Expression ofrecA-gene dependent SOS functions inSalmonella typhimurium

✍ Scribed by R. Guerrero; J. Barbé


Book ID
104759873
Publisher
Springer Netherlands
Year
1982
Tongue
English
Weight
403 KB
Volume
48
Category
Article
ISSN
0003-6072

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✦ Synopsis


Thymine starvation of RecA + Thy-strains of Salmonella typhimurium does not induce the inhibition of cellular respiration, one of the recA-gene dependent SOS functions. Nevertheless, thymine deprivation is able to produce a normal induction of prophage and thymineless death in these same strains. However, when these mutants are treated, in the presence of thymine, with UVirradiation or bleomycin, they show a normal inhibition of cellular respiration and other SOS functions. Thus, one injurious treatment (thymine deprivation) may trigger prophage induction but not cessation of respiration, whereas another agent (UV-irradiation) may induce both. Together, these results suggest a possible discrimination in the pathways and conditions of expression of various SOS functions.


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