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Expression of α2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells

✍ Scribed by M.Beatriz S. Lopes; Christopher A. Bogaev; Steven L. Gonias; Scott R. VandenBerg


Book ID
115930110
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
683 KB
Volume
338
Category
Article
ISSN
0014-5793

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Low density lipoprotein receptor-related protein (LRP) participates in the uptake and degradation of several ligands implicated in neuronal pathophysiology including apolipoprotein E (apoE), activated ␣ 2 -macroglobulin (␣ 2 M\*) and ␤-amyloid precursor protein (APP). The receptor is expressed in a