MyoD1 and myogenin are muscle-specific proteins which can convert non-myogenic cells in culture to differentiated muscle fibres, implicating them in myogenic determination. The pattern of expression of MyoD1 and myogenin during the early stages of muscle formation in the mouse embryo in vivo and in
Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis
β Scribed by Sassoon, David; Lyons, Gary; Wright, Woodring E.; Lin, Victor; Lassar, Andrew; Weintraub, Harold; Buckingham, Margaret
- Book ID
- 109761211
- Publisher
- Nature Publishing Group
- Year
- 1989
- Tongue
- English
- Weight
- 946 KB
- Volume
- 341
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/341303a0
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## Abstract It is known that the MyoD family members (MyoD, Myf5, myogenin, and MRF4) play a pivotal role in the complex mechanism of skeletal muscle cell differentiation. However, fragmentary information on transcription factorβspecific regulation is available and data on their postβtranscriptiona