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Expression of Toll-like Receptor 2 and 4 in Inflamed Pulp in Severe Combined Immunodeficiency (SCID) Mice

✍ Scribed by Eraldo L. Batista Jr.


Book ID
116677666
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
52 KB
Volume
36
Category
Article
ISSN
0099-2399

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## Abstract C57BL/10ScCr (Cr) mice carry a deletion of the Toll‐like receptor 4 (__tlr4__) gene (i.e. they are __tlr4__^0/0^) and are thus refractory to LPS effects. Insertion of wild‐type __tlr4__ transgene into the __tlr4__^0/0^ Cr germ line endowed LPS susceptibility in the two transgenic lines