Angiogenic factors play an essential role in normal and pathologic angiogenesis, but their clinical role in acute myeloid leukemia (AML) remains unclear. We investigated the expression of Ang-1, Ang-2, Tie2, VEGF-A, and VEGF-C genes in bone marrow (BM) mononuclear cells by real-time quantitative PCR
Expression of the vascular endothelial growth factor receptors 1 and 2 in acute myeloid leukemia: incidence and feasibility of immunohistochemical staining
β Scribed by M. A. KHARFAN-DABAJA; S. A. PATEL; A. O. OSUNKOYA; K. KOJOURI; R. KAMBLE; J. YANG; M. HASHMI; H. OZER; G. B. SELBY
- Book ID
- 108701792
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 215 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1751-5521
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## BACKGROUND Vascular endothelial growth factor (VEGF) and its receptors (VEGFRs) are major regulators of angiogenesis, which plays a key role in the growth and dissemination of solid tumors and hematologic neoplasms. ## METHODS The authors measured the plasma concentrations of solu
## Abstract ## Background and Methods. VEGF proteins and their receptors are involved in tumor vessel neoformation. The third VEGF receptor, VEGFR3 (fltβ4) is important during both blood vessel development and lymphatic vessel formation. Because HNSCC preferentially metastasizes to regional lymph