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Expression of the two adult β-globin genes in mouse yolk sac and fetal liver erythrocytes

✍ Scribed by C.J. Wawrzyniak; R.A. Popp

Book ID
115851923
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
331 KB
Volume
119
Category
Article
ISSN
0012-1606

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An investigation of the correlation between the y->p-globin switch and DNA methylation was carried out. The restriction patterns obtained with methylation-sensitive and -insensitive enzymes indicated hypomethylation in the promoter region of the r-globin genes in fetal liver DNA but high methylation