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Expression of the transforming Epstein-Barr virus BARF1 gene in EBV-carrying gastric adenocarcinomas

✍ Scribed by Adriaan J. van den Brule; Axel zur Hausen; Antoinette A. Brink; Mikael E. Craanen; Jaap M. Middeldorp; Chris J. Meijer

Book ID
119425436
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
203 KB
Volume
118
Category
Article
ISSN
0016-5085

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Epstein–Barr virus (EBV)-encoded BARF1 g
Epstein–Barr virus (EBV)-encoded BARF1 gene is expressed in nasopharyngeal carcinoma and EBV-associated gastric carcinoma tissues in the absence of lytic gene expression
✍ Eri Seto; Lixin Yang; Jaap Middeldorp; Tzung-Shiahn Sheen; Jen-Yan Chen; Masashi πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 203 KB

The BARF1 gene is located in the BamHI-A fragment of the Epstein-Barr virus (EBV) genome, encodes 221 amino acids, and has activity as an oncogene. Several reports have demonstrated that BARF1 is expressed in the tissues of various EBV-associated epithelioid malignancies. However,BARF1 is thought to