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Expression of the stem cell marker ALDH1 in the normal breast of BRCA1 mutation carriers

✍ Scribed by Marise R. Heerma van Voss; Petra van der Groep; Joost Bart; Elsken van der Wall; Paul J. van Diest

Publisher: Springer US
Year: 2010
Tongue: English
Weight: 221 KB
Volume: 123
Category: Article
ISSN: 0167-6806
DOI: 10.1007/s10549-010-1005-x

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## Abstract BARD1 (BRCA1‐associated RING domain) was identified by yeast two‐hybrid screening as a protein interacting with BRCA1. Somatic and germline mutations of __BARD1__ have been detected in sporadic breast, ovarian, and endometrial cancers. The present study represents the first description