The HOM-MEL-40 antigen which is encoded by the SSX-2 gene was originally detected as a tumor antigen recognized by autologous IgG antibodies in a melanoma patient. Expression analysis demonstrated that SSX-2 is a member of the recently described cancer/testis antigen (CTA) class as it is expressed i
Expression of the ras-related rap genes in human tumors
✍ Scribed by Stèphane Culne; Birgitta Olofsson; Sylvette Gosselin; Nicole Honore; Armand Tavitian
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- French
- Weight
- 919 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
MATERIAL AND METHODS ## Cell culture Out of 10 human breast-carcinoma cell lines studied, 6 were derived from metastatic carcinoma as follows: MCF7, T47D, ZR 75-1, SKBR3
Thymosins p4 and plo are 2 structurally related polypeptides originally defined in the rat immune system. To date, no truly unambiguous functions have been formally ascribed to these small (<4.9 kDa) acidic proteins. Previous research has demonstrated relationships between expression of these genes
As part of our ongoing studies to characterize molecular alterations in a well-defined series of surgically resected esophageal cancers, we examined the expression of 2 rasregulated genes, whose products (osteopontin and cathepsin L) previously were shown to be associated with tumor invasion and met
## Abstract Epigenetic aberration is known to be important in human carcinogenesis. Promoter methylation status of __RAS__ effector related genes, __RASSF1A, RASSF2A, hDAB2IP__ (m2a and m2b regions) and __BLU__, was evaluated in 76 endometrial carcinomas and their non‐neoplastic endometrial tissue