## Abstract Abnormalities of the __p53__ gene are frequently observed in human tumors, including urinary bladder carcinoma, suggesting that __p53__ plays an important role in human carcinogenesis. However, its role in rat bladder carcinogenesis is unclear. We investigated __p53__ gene mutations and
Expression of the p53 Gene and Activation of p53-Dependent Transcription in Melanoma Cell Lines
β Scribed by O. V. Razorenova; L. S. Agapova; P. M. Chumakov
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 2005
- Tongue
- English
- Weight
- 196 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0026-8933
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Epidemiologic investigations demonstrated that arsenite exposure increases the risk of various human cancers, including skin, lung, bladder, and kidney cancers. However, oral administration of arsenite alone has failed to induce tumors in animal models, suggesting that arsenic may act t
## Abstract Experiments were undertaken to investigate a genetic event involved in leukemogenesis in adult Tβcell leukemia (ATL). For this purpose, the __p53__ gene was chosen for study, since alteration of the gene has been found in a wide variety of human cancers. Structures and expression of the
## Abstract ## Background. Although cyclooxygenaseβ2 (COXβ2) has been suggested to play an important role in carcinogenesis, the effects of tumor suppressors on COXβ2 gene expression and the combined antitumor effects of tumor suppressors and COXβ2 inhibitors have rarely been investigated. ## Met