P-Glycoprotein (PGP), a product of the multidrug resistance gene (mdr), acts as an adenosine triphosphate-dependent drug efflux system in cells. Initially, PGP was found in cancer cells, but it is now known that PGP is richly distributed in the adult brain. Passage to the central nervous system is l
Expression of the MDR1 gene product P-glycoprotein in childhood neuroblastoma
✍ Scribed by Catharina R. M. Dhooge; Barbara M. J. De Moerloose; Yves C. M. Benoit; Nadine Van Roy; Jan Philippé; Geneviève G. M. Laureys
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 148 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0008-543X
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✦ Synopsis
expression of the multidrug resistance gene (MDR1) product P-gp in neuroblastoma (NB) is still a matter of debate. In this study, the role of the expression
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